似乎永不休止的感冒 为什么一直不见好转

About a month ago Sharon Gilbert was hit with a runny nose, sore throat and a cough. The whole snotty works.
大约在一个月前，莎伦·吉尔伯特(Sharon Gilbert)出现了流涕、咽喉疼痛、咳嗽等一系列令人烦恼的症状。

A few weeks later she thought she had recovered. Then her husband Derek got sick, and bam. 'Suddenly I started getting all the symptoms [again] and it was worse,' said Ms. Gilbert, a 61-year-old writer in Charleston, Ill.
几个星期后，她觉得自己已经康复了。可是，接下来她的丈夫德里克(Derek)又病了，而且猛地一下，“突然间我开始（再次）出现所有的症状，而且这次更严重了，”吉尔伯特说道。今年61岁的她是伊利诺伊州查尔斯顿(Charleston)的一名作家。

In the winter that seems to have no end in many parts of the country, people like Ms. Gilbert have been plagued with the seemingly everlasting cold.
在美国众多冬季似乎没有尽头的地区，像吉尔伯特这样的人一直受到似乎永不休止的感冒的折磨。

That's partly because the common cold can last longer than many people think -- up to two weeks for the principal symptoms and perhaps weeks more for a cough that lingers even after the virus has been cleared away. There's also the possibility of secondary infections such as bacterial sinusitis.
一部分原因是，普通感冒的持续时间要比许多人所认为的更长——主要症状会持续长达两周时间，至于在感冒病毒已被清除后仍久不见愈的咳嗽，它可能要再持续几周时间。此外，患上细菌性鼻窦炎之类的继发性感染的可能性也存在。

And some patients might get back-to-back colds, doctors say. It isn't likely people will be reinfected with the same virus because the body builds some immunity to it. But people can pick up another of the more than 200 known viruses that can cause the common cold, some of which are worse than others.
医生说，有些患者或许会连续患感冒。人们不大可能会重新感染同一种病毒，因为人体已对它形成了一定的免疫力。然而，能引发普通感冒的已知病毒有200多种（有些病毒比其他更厉害），人们还是会感染上其中一种。

'When you hear people who have the cold that 'won't go away,' those are typically back-to-back infections of which we see a lot of in the cold weather when people are cohorting together,' said Darilyn Moyer, a physician at Temple University Hospital and chairwoman-elect of the American College of Physicians Board of Governors.
天普大学医院(Temple University Hospital)医生、美国医师协会(American College of Physicians)理事会候任主席达尔琳·莫耶(Darilyn Moyer)说：“如果你听到别人得了‘永不见好’的感冒，那通常就是连续性感染，这种情况在人们常窝在一起的寒冷季节较多见。”

Influenza may get all the attention, but the common cold is the leading cause of doctor visits, according to the National Institutes of Health. Each year, people in the U.S. get about one billion colds, and 22 million school days are lost to the stubborn viruses.
美国国家卫生研究院(National Institutes of Health，简称“NIH”)称，流感吸引了人们所有的注意力，但普通感冒才是人们就医的首要原因。美国每年约有10亿人次得感冒，学生们因顽固的感冒病毒共停课2,200万天。专家们说，成年人每年平均患两到五次感冒，学龄儿童的感冒次数则多达七到10次。老年人感染病毒的次数往往较少，因为他们已经形成了对多种病毒的免疫力。与儿童生活在一起或者工作中与儿童接触的成年人感冒较多。

Experts say adults on average get two to five colds a year; school children can get as many as seven to 10. The elderly tend to get infected less because they've built up immunity to many viruses. And adults who live or work with young children come down with more colds.
对此我是深有体会。最近一个多月来，我们家似乎就在玩讨厌的感冒传递游戏。我的丈夫得了感冒，又持续咳嗽了几周时间，我们怀疑他又传染给了我们幼小的孩子。最后我也倒下了。

Don't I know it. For more than a month now my family seems to be playing a game of pass-the-nasty-cold. My husband had a cold and lingering cough for weeks, which we suspect he gave to our infant. Finally I succumbed.
我们认为我们上幼儿园的孩子是各种病菌的传播者。就在我们大家逐渐康复时，孩子开始上日托了，把某种病毒带回了家，于是我们全都开始了新一轮明显与第一次不同的感冒。

We blamed the purveyor of all germs, our kindergartner. Just as we were all recovering, the infant started day care and brought home a virus and we're all on round two of apparently a different cold.
专家指出，病菌携带者——在我们家则是我们上幼儿园的孩子——有可能会将病菌传染给别人，而自己不会出现症状。

Experts say it's possible that the carrier of germs -- in this case our kindergartner -- can infect others without having symptoms himself.
威斯康星大学麦迪逊分校(University of Wisconsin-Madison)分子病毒学研究所(Institute of Molecular Virology)的研究员安·帕尔门伯格(Ann Palmenberg)说：“在任何时候，要是我们用棉签擦拭你的鼻子，大概都能发现它里面存在着五种不同的鼻病毒，但是你也并没有生病。”鼻病毒是引发普通感冒最常见的病毒，占成年人感冒诱因的30%至50%，而且它的种类超过了150种。

'At any given moment if we were to swab you. . .we'd probably come up with five different rhinoviruses sitting in your nose but you're not sick,' said Ann Palmenberg, a researcher at the Institute of Molecular Virology at the University of Wisconsin-Madison. Rhinovirus is the most common viral cause of the common cold, accounting for 30% to 50% of adult colds, and there are more than 150 strains of it.
帕尔门伯格博士指出，鼻病毒附着在细胞间黏附分子(ICAM)受体上以便进入壁细胞，在该受体张开时，人们才会感染病毒。

To get infected, the so-called ICAM receptors, which the rhinovirus attaches to in order to enter the nasal cells, need to be open, Dr. Palmenberg said.
她说：“鼻病毒一直都存在，问题在于你什么时候会变得易受感染。”压力、缺乏睡眠和总体的健康状况等因素会使人们更容易感染。研究人员已发现了鼻病毒的150多种菌株或基因类型，他们相信可能还存在更多。病毒在上呼吸道区体温相对较低的环境（如鼻通道、鼻窦和咽喉）中复制最快。

'Rhinos are out there all the time, it's just a question of when you are susceptible,' she said. Factors such as stress, lack of sleep and people's overall health can make them more likely to get infected. More than 150 strains or genotypes of the rhinovirus have been identified and researchers believe there are probably many more.
其他病毒（如较少见的腺病毒）能在上呼吸道与下呼吸道自我复制并附着在受体上，引发更严重的疾病。