科学美国人60秒:Microbe Breaks the Powerhouse Rules
如果你在寻找科学中尚不熟悉的生命,那去哪里寻找?查理大学的科学家们研究了宠物南美栗鼠的大便。“他们隔绝了环境中的不同的细菌——其中包括自身宠物的细菌。” 来自英属哥伦比亚大学的
Anna Karnkowska也是负责该工作的进化生物学家。“科学家们喜欢尽可能地隔绝一切外界的事物。”
They found a relative of the parasite Giardia, called Monocercomonoides. It’s eukaryotic, meaning it has organelles and a nucleus enveloping its DNA. Just like our cells, or the ones in plants, or fungi. But unlike bacteria, which don’t have those things.
他们发现了一种贾第鞭毛虫的亲戚,Monocercomonoides。这是一种真核细菌,这意味着该细菌的细胞核包围着其DNA。这就像我们的细胞,或者植物、真菌中的细胞。但是其他的细菌仅是拥有裸露的DNA。
And upon closer examination, the new critter was different from every other eukaryote known to science. Because it’s missing a key organelle—it seems to have no mitochondria.
经过细致的检测,这种新的生物与科学界中已知的其他真核细胞不同。因为这种生物似乎没有关键的细胞器——线粒体。
You probably learned in biology class that mitochondria, let’s all say it together, are the powerhouses of the cell. They charge up energy-rich molecules, when oxygen's around. But they do other stuff too: like manufacture certain essential proteins. This newly discovered microbe, and others that live in low-oxygen environments, use different, oxygen-free pathways to make energy.
在生物课上,你可能学过,细胞的能量来源是线粒体。当氧气充足的时候,线粒体会为分子提供丰富的能量。但是线粒体也有其他的功能,如制造某些必要的蛋白质。这种新发现的微生物,以及依靠氧气生存的其他的微生物,利用不同的途径利用游离氧气来制造能量。
But they usually still have mitochondria for that protein assembly job. The new bug apparently pulls off the protein-synthesis by using a system that it picked up from bacteria, in what’s known as a lateral gene transfer. The findings are in the journal Current Biology.
但是,这些生物中的一些线粒体也负责蛋白质的组装工作。很显然这种新的微生物通过从细菌中沿袭的一些系统来合成蛋白质,这也就所谓的横向基因转移。该研究结果发表在《当代生物学》杂志上。
Karnkowska says the microbe's ancestors probably had mitochondria at some point—then lost them once they’d acquired the bacterial system. And she says other microbes might share a similar story. "We know now that probably there are more of these weird things." And as this study suggests, they could be found in some weird places.
Karnkowska 表示这些微生物的祖先可能曾经也有线粒体——但是之后,在获得了细菌系统之后,这些细菌就丢失了线粒体。她还表示,其他的微生物可能也有类似的情况。“现在,我们知道可能有非常多的奇异的事情。”并且,这项研究还表明,这些事情可能会出现在一些奇怪的地方。